Regenerative Medicine

Regenerative Medicine

What does the future holds? Are advances moving slow?

Regenerative medicine consists on the use of stem cells to fix structures in the body that do not function properly due to an injury or disease.

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Group of older mature people lifting weights in the gym

Stem Cells & Osteoporosis Treatment

The use of stem cells for tissue regeneration has raised great hope in various fields of medicine, including musculoskeletal disorders such us Osteoporosis. Stem cell therapy for osteoporosis potentially augment lost mineral density by either increasing the numbers or restoring the function of resident stem cells that can proliferate and differentiate into bone-forming cells, reducing the susceptibility of fractures.

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effectiveness of stem cells treatment

Take a Breath with Stem Cells – A true Story

Studies demonstrate the effectiveness of stem cells treatment as a means of repairing the damage caused by chronic lung diseases such as COPD. The ability to offset inflammation in the lungs by getting advantage of the combined anti-inflammatory and reparative properties of stem cells can reduce the inflammatory response in individuals with this kind of disease at the same time that restore lung function.

The Stem Cells Transplant Institute in Costa Rica offer secure and high quality therapies that can change the life of our patients. For people living with chronic lung disease like COPD or Emphysema, finding effective treatment options can be challenging. COPD causes shortness of breath, fatigue and persistent coughing that can affect daily activities and makes it really hard to enjoy their life.

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FDA Unapproved Stem-Cell Clinics in the U.S

FDA Unapproved Stem-Cell Clinics in the U.S.A

The National Public Radio and The New York Times, published the past August 28th , a very interesting article that Stem Cells Transplant Institute consider important for our patients to know. FDA announced a crackdown on stem-cell clinics offering on “unapproved and potentially dangerous” treatments.

As we have mentioned on many occasions, a very valuable aspect of our clinic is that we count with legally approved therapies in Costa Rica. The lack of approval and regulation on Stem Cells Treatments in the USA can lead to fraudulent and unsafe players in the field. The Treatments Stem Cells Transplant Institute provide, are those in which initial trials have shown results and great promise for the eventual approval by the FDA.

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Costa Rica Stem Cells Services: Myths and Truths

Are therapies offered by US professionals superior?

Stem cell therapies are one of the largest segments of the regenerative medicine market. This rapidly growing sector offers a number of opportunities to physicians who specialize in this field to diversify away from traditional treatments. Stem Cells Transplant Institute in Costa Rica offers high-quality stem cells therapies like Parkinson’s disease, Alzheimer´s disease, Diabetes, osteoarthritis, knee injury, osteoporosis, myocardial infarction, multiple sclerosis, COPD, anti-aging, lupus, among others. We offer many advantages for our patients compared to the competition worldwide in terms of price, security, and accessibility.

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Stem Cells & Erectile Dysfunction

Stem Cell Therapy Allows Patients to Recover Erectile Function

Erectile dysfunction, sometimes called “impotence,” is the repeated inability to obtain and maintain an erection for intercourse; affects nearly half of men between the ages of 40 and 70 to some degree. In recent years, researchers have been working to develop stem cell therapy to restore natural sexual function. New results from clinical trials show that stem cells applied to patients with “impotence” can restore enough erectile function to allow men suffering from sexual impotence to have spontaneous sex.

Stem Cells Transplant Institute in Costa Rica has state-to-the art technologies and excellent human resource to legally apply stem cell therapies. Our goal is to offer our patients all the possibilities available to address their specific health needs in order to improve their quality of life.

The Annual Congress of the European Urology Association is Europe’s largest urological event, with specialists and affiliated medical professionals gathered for a critical assessment of clinical practices and key research developments. This year was celebrated the 32nd Annual Congress of the European Urology Association in London. From March 24th to the 28th.

The results presented at the Congress show that eight of 21 successfully recovered the sexual function. Researchers are very positive about this research; this is the first time that stem cell therapy has produced patients who recovered enough erectile function to allow intercourse.

A senior researcher at the University Hospital in Odense said: “What we have done establishes that this technique can lead to men recovering a spontaneous erection – in other words, without the use of other medicines, injections, or implants”.

The work presented at the Congress focuses on patients with physical damage, caused by prostate cancer or surgery (although there are several possible causes, including surgery, high blood pressure, diabetes, cardiovascular disease and psychological problems).

The researchers used stem cells extracted from abdominal adipose tissue via liposuction; stem cells were then injected into the cavernous body of the penis. The results show that none of the 21 men reported significant side effects over the trial period, or in the following year.

Six months after treatment, eight of the 21 patients reported that they had regained enough erectile function to achieve penetrative sexual activity. This improvement has been maintained for one year, indicating that this treatment may confer long-term benefits.

In addition, using the International Erectile Function Index (IIEF) questionnaire to measure erectile function, where the average for men with “normal” sexual function is about 25; they found the whole group of 21 patients reported that their score had increased from 6 before the stem cell transplantation surgery, to 12 after 6 months. Better than this, in the group of men who recovered sexual function, the IIEF score increased from 7 to 14 (enough score to enable men to have a spontaneous erection sufficient for penetrative sex).

Leading researchers say the technique has been tested in animal work, but this is the first time that stem cell therapy has allowed patients to recover enough erectile function to allow intercourse.

This technique promises to be a long-term solution for patients suffering from erectile dysfunction, who have not seen beneficial effects of traditional medicine, such as PDE5 inhibitors (Viagra and Cialis), injections, or penile implants.

In technical terms, the procedure consists of extracting stem cells from fat tissue via liposuction and then injecting stem cells with a syringe into the penis, where they spontaneously begin to change in nerve and muscle cells as well as endothelial cells that line blood vessels. Patients are under general anesthesia while all this happens, and they are discharged from the hospital the same day! At Stem Cells Transplant Institute in Costa Rica, we are more than happy to help you stay in touch with the latest advances in stem cell therapies; we believe that this is only the begging of the development of effective and long-term solutions for patient´s specific needs. Do not hesitate to contact us for any questions you have.

Stem Cells & Diabetes

What is Diabetes Mellitus and How can Stem Cells be used?

The global incidence of diabetes mellitus has increased dramatically over the past few years and continues to rise. The quest for curative therapies that normalize sugar blood levels and provide independence from exogenous insulin therapies impacts patients with type 1 diabetes, and and type 2 diabetes who have a functional deficiency in insulin production. Stem cells hold tremendous potential as a source of insulin-producing cells and as a method of studying the disease. Researchers are looking for ways to diagnose people earlier, prevent their diabetes from getting worse, and to more effectively treat the disease.

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Stem Cells & Anti Aging

Stem cells collected from your own fat, a new anti aging treatment

Population aging is transforming economies and societies over the world. Over the next 20 years, the U.S. population may grow by about 60 million. Half of the population will be over the age of 65. Many institutions are studying the role of stem cells in aging and anti aging processes.

Aging is a complex process that occurs when the self-renewing capacities of our body decline. The ability of stem cells to multiply and replace aging cells with new cells diminishes over time and stem cell reserve of our body gradually decreases. For example, in healthy individuals, skin youthfulness is maintained by epidermal stem cells which self- renew and generate daughter cells that become new skin, this epidermal stem cells quantity decreases over time. Some facts like bad habits, stressful lifestyle, inadequate nutrition, and poor environment accelerate our body decline.

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Breathing better with Stem Cells

Stem Cells & Lung Health

Stem Cell therapy is currently being investigated as a promising therapeutic approach for a number of incurable, degenerative lung diseases. Stem Cells Transplant Institute in Costa Rica is always offering to our patients up-to-date information about this new medical trend. We want to help you open your mind to this new world of possibilities, responsibly and transparently.

Chronic Obstructive Pulmonary Disease is a term used to describe progressive lung diseases including emphysema, chronic bronchitis, refractory asthma, and some forms of bronchiectasis. This disease is characterized by increasing breathlessness, which leads to reduced lung function and eventually respiratory failure.

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Stem Cells Treatment in Costa Rica One of the best health care in the world 2017

An article published in January 5th 2017 by the Consumer News and Business Channel (CNBC) an American basic cable, ranked as the 19th most valuable cable channel in the United States, confirms that Costa Rica is one of the four countries with the best health care in the World. The article was originally published by International Living, a worldwide program created to share experiences, languages, and customs with those from different traditions, with the goals of broadening horizons and advancing peace.

Stem Cells Transplant Institute located in Escazú, Costa Rica, offers state-of-the-art technologies in Stem Cells. We have the best equipment, human resource and one of the best health care systems in the world for you to have your stem cells treatment procedure.

Lets take a look to some important points that media highlight about Costa Rica´s heath care system (check it at

More than 40,000 Americans travel each year to Costa Rica to seek medical and dental treatment because of the outstanding reputation of Costa Rica. These “medical tourists” have discovered that this little Central American country has high quality healthcare available at a very low cost compared with their home country. The medical tourism is increasing each year as more and more patients find out the advantages of coming to Costa Rica.

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Restoring sight with Stem Cells…a light at the end of the tunnel.

Stem Cells Treatment

Restoring sight with Stem Cells…a light at the end of the tunnel.


Retinal degeneration represents a group of blinding diseases that are increasingly impacting the health and well being of patients all over the world. Many people in the United States will suffer from vision loss or blindness due to the age-related macular degeneration, the most common cause of irreversible vision loss and blindness in older adults.
Sight gradually worsens as the nuclear layer of light-sensitive photoreceptor cells in the eyes is degraded. Macular Degeneration is a progressive ocular disease of the part of the retina, called the macula, which enables people to visualize faces, read and drive. The disease initially causes distortion in central vision, and eventually leads to legal blindness.

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Are patients actually walking again?

Stem Cells Therapies and Stroke
Are patients actually walking again?

Around 800,000 people suffer a stroke each year in the United States, 85 percent of all strokes are ischemic (a clot forms in a blood vessel supplying blood to part of the brain, with subsequent intensive damage to the affected area). After the event loss of function incurred depends on exactly where within the brain the stroke occurs, and on its magnitude.

According to the National Stroke Association, around 2 in every 3 stroke survivors will have some form of disability, and stroke is the leading cause of disability among American adults.

Although approved therapies for ischemic stroke exist, current treatments are very limited and usually have no benefits in chronic patients.

The “gold standard” treatment for ischemic stroke is tissue plasminogen activator (tPA); it works by dissolving the blood clot that is blocking blood flow to the brain. However for the treatment to be effective it must be applied within a few hours of the event – a time period that is often exceeded by the time it takes for a patient to arrive at the hospital.

Stem Cells treatment opened a new world of possibilities for patients that seemed to have no hope. Patients disabled by a stroke have demonstrated substantial recovery long after the event when modified adult stem cells were injected into their brains.

A professor and chair of neurology at Stanford University School of Medicine in Palo Alto, CA, and colleagues publish the findings of a trial in the journal Stroke. While the trial only included a small number of stroke participants, the results were very positive. Some health experts considered the findings could lead to “life-changing treatments” for stroke patients.

At first the trial was designed to test the treatment safety, but patients improvement was statistically significant and clinically meaningful. Their ability to move around recovered visibly after more than six months of the stroke. Patients today are not expected to see any further recovery. This is something never seen before!

Injecting adult stem cells directly into the brains of chronic stroke patients improved their scores on a 100-point scale for evaluating mobility – with 100 being completely mobile – patients improved on average by 11.4 points (a margin considered to be clinically meaningful for patients). They also had improvements in strength, ability to walk, coordination, the ability to use hands and the ability to communicate.

The Newscientist published last June the story of a 71-year-old woman who could only move her left thumb at the start of the trial; “She can now walk and lift her arm above her head.” – Said a neurosurgeon at Stanford University
But how it works? Experts injected around 2,5 to 10 million stem cells taking from the bone marrow through a borehole in the skull into regions of the brain that control motor movements. “The cells seem to recover their ability to repair and their adaptability as in the brain of a baby,” – Said the expert

This is very encouraging news for the field of stem cell research and especially patients with established disability as a result of stroke, where this is no proven treatment to aid recovery.

Today there are around 30 similar trials in progress. The researchers believe that such a treatment may not be limited to stroke patients – it has the potential to treat a number of brain injury-related conditions. This could revolutionize our concept of what happens after not only stroke, but also traumatic brain injury and even neurodegenerative disorders.

Currently, the United States is still in clinical trial phase, therapies are not legally approved into the country yet, despite all the benefits achieved. That is one of the reasons why medical tourism is growing fast.

Stem Cells Transplant Institute in Costa Rica is a pioneer in Stem Cells Treatment, Costa Rica ranks high as one of the top 5 Medical Tourist destinations in the world, receiving close to 45,000 medical tourists each year. We aim to help you get more information about stem cells therapies applications available for your specific need. Don’t hesitate to contact us. There is very interesting information in this field that we want to share with you.

Stem Cells: The Past, The Present or The Future?

Medicine is an ever-evolving field. New breakthroughs are being made all the time and many discoveries in medicine have changed the way of human living.

If you’ve ever visited a museum of naval history, you have definitely seen a display that shows how they used to do surgical procedures on board ships in the 1800s. Amputations were done on a table, with the injured man biting on a piece of wood to stop from screaming. Luckily, the late 19th century saw the discovery of anesthesia, which numbs all sensation in the patient. Some early anesthetics were cocaine and chloroform, but these two had potentially lethal side effects. Fortunately, today’s anesthetics are both effective and safe.

When we talk about Stem Cells many people think of it as The Medicine of the Future and it definitely has opened a new world of treatment options and it might change the way we know medicine today. But, there is something that seems to be misunderstood; Stem Cells are not just a medicine of the future, but a novel treatment available today.

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Pain Management

Living without pain, living better

It is estimated that 100 million adults in the US, experience chronic pain. The need for effective treatments continues to grow. The goal of pain management is to increase function, improve quality of life and reduce one’s sense of suffering. One of the major challenges is finding treatments that relieve pain and allow a person to function normally. While stem cells may hold the key to many future treatments, they’re also being investigated as a way to help patients find treatments to treat pain and other symptoms.

Many pain-related diseases like degenerative and inflammatory conditions have very limited treatments currently and the pain has gained the battle for many patients that lost their hope to recover their normal life.

Stem Cells Transplant Institute in Costa Rica specializes in the use of adult autologous stem cells harvested from your own fat tissue and bone marrow. The stem cells are obtained from your own adult tissues and afterwards are injected back into the bloodstream intravenously. The possibilities of rejection are almost absent and the benefits are more and more according to the investigations results.

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Fat Derived Stem Cells vs Bone Marrow Derived Stem Cells

Did you know your own body fat and bone marrow contains a large amount of stem cells? Bone Marrow and Adipose tissue contain adult stem cells, these cells are thought to be “mother cells” found among differentiated tissue or organ. The adult stem cell can renew itself and can differentiate to almost all of the major specialized cell types. The primary roles of adult stem cells are to maintain and repair the tissue in which they are found.

Research on adult stem cells has generated a great deal of excitement. Scientists now have evidence that stem cells exist in many other tissues like the adipose tissue, brain and hearth; thanks to these findings investigators and clinicians are studying the use of stem cells in transplant. Both marrow and fat derived stem cells are effective and have the potential to differentiate into mature functional tissues.

Adult hematopoietic stem cells from bone marrow have been widely used in transplants for more than 40 years. Stem Cells Transplant Institute in Costa Rica specializes in the use of stem cells derived from bone marrow and adipose tissue, to treat many inflammatory and degenerative diseases. These cells are taken from your own tissue, so the security is very high and the possibilities of rejection are almost null.

But, Which kind of stem cells are actually better?

At Stem Cells Transplant Institute in Costa Rica, this is a question we receive from our patients, and we understand that anyone considering receiving stem cell treatment will want to choose the option that promises the best results. However, most patients are surprised to learn that in terms of clinical results, there is no evidence to substantiate significant difference between the use of bone marrow derived cells or fat derived cells, the clinical outcome for both is practically the same.

It´s important to mention that fat derived cells are based on more recent discoveries, so there are fewer studies using these cells although there are some advantages depending on the treated disease, due to the profound anti-inflammatory effects. Another important advantage is their abundance, fat tissue contains hundreds, even thousands of times more stem cells than bone marrow and therefore there is no need for culturing.

At Stem Cells Transplant Institute, Dr Mesen will guide you to your best option. Although clinically, the outcomes are very similar, there are some differences in the extraction, cell preparation, deployment and recovery according to the cell type.

Regarding to the extraction, in the case of stem cells removed from bone marrow the surgical procedure must be performed under general anesthesia, and the process involves inserting a needle into the hipbone to extract the stem cells. In the case of stem cells removed from fat, the procedure is performed under local anesthesia. The process involves a mini-liposuction to obtain patient´s own fat usually from the abdominal or flank area. The extraction is relatively painless and its performed in a short period of time.

With respect to the cell preparation, bone marrow stem cells need first to be cultured over several days to be delivered into the patient, while stem cells isolated form fat uses a technology that yields a high number of viable stem cells and can be used almost immediately.

Talking about cell delivery into the patient, stem cells obtained from bone marrow are injected through arteries, veins, into spinal fluid, directly into joints or organs or subcutaneously. Stem cells obtained from fat, are deployed back into the patient’s body directly into joints or intravenously.

Finally, we can find differences in the recovering process, downtime from stem cell therapy using bone marrow extraction can take several weeks, while patients who receive stem cell therapy requires only a few hours.

In conclusion, one of the most promising treatments for numerous types of injuries and diseases is stem cell therapy. The most common way that stem cells are currently used is via harvesting of adult stem cells from the patient’s own bone marrow and fat tissue, and injecting them at the site of damage or intravenously. The main function of these cells is to repair any damaged cells.

In terms of effectiveness of stem cell therapy, bone marrow stem cells and adipose-derived stem cells are very similar, but we can find differences in terms of extraction, cell preparation, deployment and recovery.

Stem Cells Transplant Institute in Costa Rica is a pioneer in stem cells treatment and we´ll be more than happy to answer all the questions you have about this new medical trend. We offer high quality services in one of the most beautiful places in the world.

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