“A man begins to die when he ceases to expect anything from tomorrow”
····Discovering the secret of stem cells, represent a change in the vision of living organisms···
It is extraordinary the potential of stem cells therapies to revolutionize medical care, diseases such us diabetes, myocardial infarction, Alzheimer´s disease, Parkinson´s disease, rheumatoid arthritis, systemic lupus erythematosus and others, which today have very limited conventional treatments, could be potentially curable. Investigations results are very promising and they are getting more acute and specific over time.
Stem cells are being studied under clinical investigations that have been submitted to and allowed to proceed by FDA. Relevant professionals like Dr. McQuillan formed the Ageless Regenerative Institute in conjunction with a team of experts in stem cell therapies. This expert team has developed an approved methods and protocols for the harvesting and isolation of adipose derived stem cells for autologous reimplantation.
Many countries over the world are already using stem cells therapies with great results. Stem Cells Transplant Institute under the direction of Dr. Mesén has the mission to provide to its patients the highest standards of quality, service, lawfulness, honesty and human resource, so they can opt for these life-changing therapies; as well as to contribute with the expansion of this medical trend.
The belief that there exists an undifferentiated cell which can be programmed into another type of cell forms the basis of stem cell biology. Today, stem cells treatments have become a reality. The capability of stem cells to regenerate organs and tissues opens a wide spectrum of treatment possibilities for many diseases that were considered incurable.
There is an increasing interest in using stem cells in treatment of degenerative diseases such as Parkinson’s disease, Alzheimer´s disease, diabetes, osteoarthritis (OA), knee injury, osteoporosis, myocardial infarction, and multiple sclerosis for which there is no curative therapy.
About Stem Cell
Stem cells are distinguished from other cell types by two important characteristics. First, they are unspecialized cells capable of renewing themselves through cell division. Second, under certain physiologic conditions, stem cells can be induced to become tissue- or organ-specific cells with special functions. In some organs, such as the gut and bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues.
Nowadays, we know that stem cells are not only in the umbilical cord, but we can find them in all human body tissues. Stem cells are now isolated from adult specialized cells and there has been a continuing expansion in the number and type of stem cells under study.
Classification of stem cells
Stem cells can be classified into four broad types based on their origin. Stem cells from embryos; stem cells from the fetus; stem cells from the umbilical cord; and stem cells from the adult. Each of these can be grouped into subtypes. For example, adult stem cells are divided in germline and somatic (hemopoietic, mesenchymal, liver, epidermal, neuronal, eye, gut..)
Stem cells can also be classified according to its plasticity in totipotent, pluripotent, multipotent and unipotent cells. Totipotent stem cells have the potential to generate all the cells needed for human development, plus the extra embryonic, or placental, cells. Embryonic cells within the first couple of cell divisions after fertilization are the only cells that are totipotent. Pluripotent stem cells can give rise to all of the cell types that make up the body; embryonic stem cells are considered pluripotent. Multipotent stem cells can develop into more than one cell type, but are more limited than pluripotent cells; adult stem cells and cord blood stem cells are considered multipotent. They are found in specific organs and can only become cells within that organ; for example, multipotent stem cells in the brain can become nerve cells or other brain cells. These cells do have the potential to maintain and repair particular organs and tissues. Unipotent stem cells can be differentiated along only one lineage.
Benefit of Stem cells therapies
Stem cells therapies have been expected to bring substantial benefit to patients suffering a wide range of diseases and injuries. For example, benefits of cells transplantation for patients needing reconstruction of their immune systems, would apply to stem cell transplants of other cell types, and optimism has been high for the utilization of pluripotent stem cell types for a variety of applications.
Clinical investigations using stem cell products in regenerative medicine are addressing a wide spectrum of conditions using a variety of stem cell types. Many stem cells administered show transient presence for a few days with trophic influences on immune or inflammatory responses.
Stem cells and their differentiated progeny offer great hope for treating disease by providing an unlimited source of cells for repairing or replacing damaged tissue. Initial studies suggested that, unlike ‘normal’ transplants, specific characteristics of stem cells enabled them to avoid immune attack, providing more effective transplants.
Why patients with Osteoarthritis of the knee are choosing stem cell transplantation instead of surgery?
- Stem cell transplantation promotes self-healing
- Stem cell transplantation is less invasive than surgery
- Stem cell transplantation is a more “natural” treatment without the use of plastic or metal
- After stem cell transplantation patients recover quicker