Stem cells news

Wharton’s Jelly Mesenchymal Stem Cells
Stem cells

Researchers Review the “Biological Properties and Therapeutic Potential” of Wharton’s Jelly Mesenchymal Stem Cells (MSCs)

Researchers from Italy conducted a literature review of 83 articles about the biological properties and therapeutic potential of mesenchymal stem cells derived from Wharton’s Jelly of the human umbilical cord, and published the key learnings in 2019 in the International Journal of Stem Cells.1 The following is a summary of their findings. You can access the full article at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657936/ Studies indicated WJ-MSCs could be used to treat:1-7 Neurological disorders Kidney injury Lung injury Orthopedic injury Liver injury Certain cancers The Following Properties Make WJ-MSCs Optimal Candidates for Allogenic Transplant1 WJ-MSCs have potent regenerative and immunomodulatory capabilities WJ-MSCs are capable of immune suppression and immune avoidance WJ-MSCs express very low levels of Human Leukocyte Antigen class I and zero expression of Human Leukocyte Antigen DR WJ-MSCs induce expansion of regulatory T cells and in vitro, do not generate immune responses from regulatory T cells WJ-MSCs produce tolerogenic Interluekin-10 and Transforming

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Stem cells

Is Michael Schumacher Receiving Stem Cell Treatment?

The French daily newspaper, Le Parisien, reported the Formula One legend, Michael Schumacher is receiving stem cell therapy at the Georges-Pompidou Hospital in Paris, France. Michael Schumacher suffered a traumatic brain injury after a devastating ski accident six years ago. Michael Schumacher, a retired German racing driver, is a seven-time Formula One champion, Ferrari’s most successful Formula One driver, and considered by many to be the greatest Formula One racer of all time. On December 29, 2013, Schumacher was skiing in the French Alps with his son when he sustained a traumatic brain injury after hitting his head on a rock. Following his injury, he underwent two surgeries and was put into a medically induced coma. Since 2014 he has been undergoing rehabilitation at his private residence. It has been reported that he is paralyzed and has difficulty communicating, but is slowly improving. What is Stem Cell Therapy? Stem cell

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Stem Cells for Cerebral Artery Ischemic Stroke
Stem cells

Clinical Trial Shows Human Umbilical Cord Blood to be Safe for the Treatment of Cerebral Artery Ischemic Stroke

A hallmark clinical study by physicians at Duke University and the University of Texas, published in Stem Cells Translational Medicine in 2018, showed IV infusion of human umbilical cord stem cells to be safe for the treatment of Cerebral Artery Ischemic Stroke.1 More than 85% of all strokes are ischemic strokes. Ischemic stroke is one of three types of stroke and occurs when the artery that supplies blood to the brain is blocked, reducing blood flow and oxygen to the brain. If blood circulation is not restored quickly, permanent brain damage occurs. Ischemic stroke can cause death or long-term disability and the only approved treatment is tissue plasminogen activator (tPA). TPA breaks up clots but to be effective it must be given within four hours from the start of the stroke and cannot be given after five hours. Additionally, it cannot be given to individuals with a history of hemorrhagic

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Cardiovascular

The Benefits of Allogeneic Mesenchymal Stem Cells for the Treatment of Cardiovascular and Neurodegenerative Disease

Mesenchymal stem cells are multipotent stromal cells that have the ability to differentiate, or become, a variety of cell types, including bone cells, cartilage cells, fat cells, and muscle cells. Mesenchymal stem cells (MSCs) are ideal for treating many kinds of injuries and disease, and can be derived from many different kinds of tissue including; bone marrow, adipose tissue, cord blood and cord tissue. Studies have been conducted using MSC derived from each of the different types of tissue and there is a lot of debate about what type of MSC is best for the treatment of different conditions. Most research has been conducted with MSCs derived from bone marrow and these cells have become the “gold standard” when discussing stem cell therapy. However, researchers are learning more everyday about the different properties of MSCs depending on what type of tissue they are derived from and there are many factors

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Degenerative Spine Disease

Stem Cell Therapy: The Future for Degenerative Spine Disease

Degenerative disease of the lumbar spine is a primary cause of disability worldwide affecting at least 266 million people each year. Degenerative disease of the lumbar spine is an umbrella term used to describe different types of back pain including spondylolisthesis, spinal stenosis and disc degeneration.1,2 Degenerative disc disease in a condition in which damage to the spinal disc causes pain that can range from nagging to disabling and is the second leading cause of opioid prescriptions in the United States. For patients with severe degenerative disease, surgery may be considered as a treatment option, but surgery is invasive, risky, costly, and its effectiveness is unclear. For this reason, stem cell therapy is quickly becoming a preferred treatment option. Current Research The Stem Cells Transplant Institute in Costa Rica, recommends mesenchymal stem cells derived, cultured, and expanded from umbilical cord tissue, for the treatment of degenerative disc disease. A paper

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Stem cells

Wharton Jelly Stem Cells for the Treatment of Chronic Diabetic Skin Wounds

Results, of a study published in the Journal of Cosmetic Dermatology in May, 2019, showed human umbilical cord derived Wharton’s jelly mesenchymal stem cells can accelerate the repair and healing of chronic skin ulcers. Diabetic skin ulcers are painful, slow to heal, and require medical attention. Consistently high levels of blood sugar cause nerve and blood vessel damage, reduce circulation, and alter the skin’s structure causing harmless wounds to become open sores called diabetic ulcers. If left untreated, diabetic skin ulcers can become infected causing tissue death and ultimately require amputation. A diabetic ulcer is an open sore or wound and most commonly presents on the foot that does not progress through the normal healing process. Approximately 15% of patients with diabetes will develop a foot ulcer and approximately 6% of people will require hospitalization due to an infection or other wound related complication. Researchers at Shiraz University of Medical

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Stem cells

Benefits of Wharton’s Jelly Mesenchymal Stem Cells (MSCs) When Compared to Adipose or Bone Marrow Derived MSCs

Mesenchymal stem cells (MSCs) are adult stem cells that are able to differentiate into a wide variety of cell types. These cell types include bone, muscle, fat, cartilage, umbilical cord blood, and umbilical cord tissue. The benefits of MSCs are attributed primarily to the secretion of factors including cytokines and growth factors, which produce immunomodulatory and anti-inflammatory effects and stimulate angiogenesis. The gold standard tissue for mesenchymal stem cells has been bone marrow tissue, however, the results have been mixed and retrieving the stem cells from a patient’s own bone marrow is invasive and can be painful. Wharton’s jelly mesenchymal stromal (stem) cells are harvested from umbilical cord tissue and are considered by many regenerative experts to have the most potential for effective cell-based therapy with the added benefit of being far easier and less invasive to retrieve. Additional Benefits of Wharton’s jelly MSCs More abundant than both bone marrow

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Stem cells

Japan Approves Stem Cell Therapy for Spinal Cord Injury

Results, from a study at Sapporo Medical University in Japan, showed bone marrow derived stem cell therapy to be safe and effective for the treatment of spinal cord injury. Japan approves the first commercially produced stem cell product, Stemilac injection, for the treatment of spinal cord injuries. Stemilac was developed jointly by Nipro and Sapporo Medical University and is the world’s first approved marketed product for stem cell therapy, available only at the Sapporo Medical University in Sapporo, Japan. “This is an unprecedented revolution of science and medicine, which will open a new era of healthcare,” says oncologist Masanori Fukushima, head of the Translational Research Informatics Center, a Japanese government organization in Kobe that has been giving advice and support to the project for more than a decade. Weblio website Trial Design In an open-label trial, researchers in Japan evaluated autologous bone marrow derived stem cells in 13 patients who

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Stem cells

How Does Stem Cell Therapy Work?

As the evidence of the clinical efficacy of stem cell therapy continues to grow, the physicians at the Stem Cells Transplant Institute receive hundreds of questions daily from people asking the same question: What happens to the stem cells once they are injected into the body?  There are 2 theories, that are not mutually exclusive: The undifferentiated stem cells arrive at the site of injury where they differentiate and become the type of cells specific to the tissue at that site. For example, when the stem cells reach the área of damaged cartilage, they differentiate into chondrocytes (the cells that form cartilage). Most adult tissue regenerates tissue naturally, however, it may not contain or regenerate a sufficient supply of cells to heal the injury or damage. Every person has a limited number of naturally occuring stem cells and the population of stem cells decreases due to age, environmental toxins and

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Stem cells

Regenerative Medicine: Which type of stem cells are best?

To understand which type of stem cell is best, it is necessary to dive a bit deeper into the science of stem cells and Regenerative Medicine. Regeneration is the ability of the human body to heal itself.  Regenerative medicine is the clinical application of regeneration. Two of the main sources of regenerative medicine are stem cells and growth factors, which stimulate and enhance stem cell and tissue regeneration. What are Stem cells? Stem cells are a type of undifferentiated cell that have the ability to differentiate, or change, into specific and specialized cell types. Adult stem cells are a type of undifferentiated cell found in a tissue or organ. It can renew itself and can differentiate into some or all of the major specialized cell types; replacing cells that are dying, and releasing molecules that enhance the repair of damaged tissue due to disease, trauma and aging. Two main characteristics

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Stem cells

Human Umbilical Cord Tissue Mesenchymal Stem Cells the New “Gold Standard” for Stem Cell Therapy

Regenerative medicine may be the best hope for patients with a chronic disability or disease. Stem cells are being used to treat neurological, cardiovascular, autoimmune and orthopedic conditions as well as spinal cord injuries, severe wounds, erectile dysfunction and the list goes on. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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Stem cells

Transplanted bone marrow-derived endothelial stem cells delay the progression of ALS

According to a report, published by researchers from the University of South Florida on March 27, in Scientific Reports, transplantation of human bone marrow-derived endothelial progenitor cells (EPCs) into mice with similar symptoms of amyotrophic lateral sclerosis (ALS) helped more motor neurons survive and slowed disease progression by repairing damage to the blood-spinal cord barrier (BSCB). Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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Autologous Stem Cells
Multiple Sclerosis

Autologous Stem Cell Transplantation, First Line Therapy in “Aggressive’ MS

The evidence keeps growing; autologous hematopoietic stem cell transplantation is a safe and effective treatment for patients diagnosed with multiple sclerosis. Most recently, data presented in October, 2018 at the 34th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) in Berlin, Germany, showed autologous hematopoietic stem cell transplantation (AHSCT) was a safe and highly effective treatment in patients with ‘aggressive’ multiple sclerosis. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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Umbilical Cord Stem Cells Therapy
Stem cells

The Stem Cells Transplant Institute in Costa Rica Now Offers Umbilical Cord Stem Cells

Stem cell therapy, in combination with growth factors and antioxidants, has been shown in clinical trials to be one of the best therapeutic options for a number of diseases including but not limited to: Alzheimer’s disease, Parkinson’s disease, osteoarthritis, rheumatoid arthritis, lupus, cardiovascular disease, diabetes, multiple sclerosis, spinal cord injury, burns, erectile dysfunction, and COPD as well as a natural method to fight other signs and symptoms of aging.  Stem cell therapy improves cell regeneration and aids in tissue healing and repair. At the Stem Cells Transplant Institute in Costa Rica we offer Stem cells derived from adipose tissue Stem cells derived from bone marrow Now Available! Umbilical cord-derived stem cells What are Stem Cells? Stem cells are a type of undifferentiated cell that have the ability to differentiate, or change, into specific and specialized cell types. Stem cells can be guided into becoming a specific type of cell allowing physicians trained in

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Umbilical Cord Stem Cells in Costa Rica
Stem cells

Umbilical Cord Stem Cells: Once Considered a Waste Product, Now Saves Lives!

Stem cells are unspecialized cells that differentiate into specialized cells and are the basis of all tissue and organ cells of the body. There are three two main sources of stem cells used to treat injuries and chronic diseases: adult stem cells, and umbilical cord stem cells. Adult stem cells are found in various tissue in the human body, but the two most common types are bone marrow derived stem cells and adipose derived stem cells. Typically stem cell clinics use one or two types of stem cells to treat disease, but the Stem Cells Transplant Institute offers treatment using bone marrow derived stem cells, adipose derived stem cells or umbilical cord stem cells.

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Stem cells

Stem Cell Treatment: Choosing a Qualified Specialist

Your choice for regenerative medicine and stem cell treatment has the potential to change your life. Stem cell therapy can improve your quality of life by offering relief to patients suffering from chronic pain, difficult to heal injuries, and certain chronic conditions. However, all procedures have some risk, even under the safest conditions. You have to consider what can potentially go wrong and use that information to help you pick the most qualified clinic and physician. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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Stem cells

STEM CELL TRANSPLANTATION: STAY YOUNG & HEALTHY!

Dr. Leslie Mesen and the Stem Cells Transplant Institute were recently featured in Wellness Magazine, Austria’s biggest premium health magazine. The article “Stem Cell Transplantation: Stay Young & Healthy” was made available to readers in May while the printed article will be available in the June issue. For the benefit of our English and Spanish speaking readers, below is the translated article. http://www.stemcellsgroup.com/issca-leslie-mesen/

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Stem cells

New Research Shows Stem Cell Therapy May Help Women with Primary Ovarian Insufficiency

Primary ovarian insufficiency (POI), also called premature ovarian failure, occurs when your ovaries stop functioning normally before the age of 40. When the ovaries stop functioning normally they no longer produce sufficient amounts of estrogen and will not store and release eggs regularly. Frequently women with POI are diagnosed with premature menopause but they are not the same thing. Women with primary ovarian insufficiency will continue to have irregular periods for years and may become pregnant, although infertility is one of the symptoms of POI. Women with premature menopause stop having periods and do not have the ability to become pregnant. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills

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Stem cells

Our position regarding the alert given to Costa Rican population about stem cell treatment by the Costa Rican College of Physicians and Surgeons

A series of reports have recently appeared in electronic, national, and international media sources, citing a warning by the College of Physicians and Surgeons of Costa Rica, about abuses that may be taking place in our country by unscrupulous clinics using stem cells. According to news sources, some of these clinics are offering “miracle therapies” to patients, without any clinical or scientific data to support the therapies. 

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Stem cells

Myth vs Fact: Explaining the controversy of stem cell therapy

Engage in a discussion about stem cell therapy and you could find yourself in an emotionally charged situation. Stem cell therapy might be the most controversial topic in medicine today, but the controversy spreads beyond medicine and crosses into political and religious beliefs. Much of the contention is the result of incorrect and misleading information due to personal bias; this has slowed and, in some cases, stopped the critical research necessary to advance this field of medicine. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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Stem cells

Mesenchymal Stem Cells Heal a Large Foot Ulcer Resulting From a 30,000 Volt Electrocution

Abstract: Juan, a 45 year-old electrician,suffered a 30,000 volt shock when his left arm contacted a high tension power line. The current travelled down the back of his left leg and exited via a 12cmx10cm wound on the dorsal aspect of his left foot leaving the underlying structures exposed. He subsequently fell from the platform and spent 2 months in the hospital. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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Stem cells

Leslie Mesen, MD is named the International Society of Stem Cells Application (ISSCA) Director for Central America and the Caribbean

The International Society for Stem Cell Application (ISSCA) promotes excellence in the field of Regenerative and Stem Cell Medicine. In more than 25 countries, the organization partners with academic centers and medical schools and assists members with education, publications and certifications.  As a leader in the field of regenerative medicine, the ISSCA named Dr. Leslie Mesen, Director for Central America and the Caribbean. In his new role, Dr. Mesen will help the ISSCA to be:

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Stem cells

Start the new year looking and feeling younger!

Stem cells can slow or reverse the signs of aging, by regenerating and repairing tissue and organs damaged by stress and environmental toxins, improving immune function and reducing inflammation. The Stem Cells Transplant Institute, in Costa Rica, uses adipose derived stem cells to treat the signs and symptoms of aging. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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Stem cells

Stem cells vs Opioids to Treat Back Pain

Medical research has shown stem cells have enormous potential to keep us healthy and aid in healing. Millions of back pain sufferers can finally find pain relief with stem cell treatment. A local injection of stem cells could become the crucial tool for eliminating the use of opioids, the standard of care that is currently killing thousands of patients. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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Stem cells

Extending Life with Stem Cells?

Stem Cell Implants Make Fresh Neurons in the Brain Researchers and scientists have slowed down the aging process by using stem cells; stem cells may offer us a new way to combat age-related diseases and extend the human lifespan. The Stem Cells Transplant Institute in Costa Rica wants to keep our patients informed by sharing with you the latest news and advances in regenerative medicine. This article will review how scientists are using stem cells to extend and improve life. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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Stem cells

Regenerative Medicine

What does the future hold? Are advances moving slowly? Regenerative medicine consists of the use of stem cells to fix structures in the body that do not function properly due to an injury or disease. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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Stem cells

Are Stem Cells able to speak? Amazing Studies and Facts

Stem cells are not able to speak as humans do, but they can definitely communicate to other cells for very important and specific processes according to Information provided by Medical University of Vienna. Read on to learn more about the “language of stem cells”! Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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Stem cells

FDA Unapproved Stem-Cell Clinics in the U.S.A

On August 28, The National Public Radio and The New York Times, published a very interesting article that we at the Stem Cells Transplant Institute want to make you aware of. The FDA announced a crackdown on stem-cell clinics in the United States that are offering an “unapproved and potentially dangerous” treatment. A very valuable aspect of the Stem Cell Institute in Costa Rica, is we provide only legally approved therapies. The lack of approval and regulation on stem cell treatments in the USA can lead to fraudulent and unsafe practices. The Stem Cells Transplant Institute provides treatments that have data showing positive results and great promise for the eventual approval by the FDA. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas,

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