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Lupus

Systemic Lupus Erythematosus

Introduction Systemic Lupus Erythematosus (SLE) is an autoimmune disease. The exact cause is still unknown, and the severity can vary person-to-person. Because the cause is still unknown, treatment is still difficult. Research is ongoing to develop better treatment options. What is SLE? SLE is an autoimmune disease that affects multiple organ systems. While the exact cause is still unknown, scientists believe it is related to genetic, hormonal, and environmental factors. In particular, the genes HLA-DR2 and HLA-DR3 are commonly present in people with SLE. Certain proteins, like C1q, C2, and C4 are also deficient in 10% of people with SLE. Scientists have found that certain hormones increase the likelihood of developing SLE. People with more estrogen due to oral contraceptive use, postmenopausal hormonal replacement therapy, and endometriosis have an increased risk of SLE. Lastly, environmental factors may play a role in developing this condition. UV light, bacterial and viral infections,

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Lupus

Stem Cell Therapies for Lupus

Introduction Lupus, formally known as Systemic Lupus Erythematosus (SLE), is an autoimmune disease. The exact cause is unknown, and current treatments vary in regards to success. Current research is ongoing to determine the best treatment options. Stem cells have shown some promise in their early stages. The research is still in its beginning stages, and more research is needed to shed more light on the issue. What is Systemic Lupus Erythematosus? SLE is an autoimmune disorder, more commonly known as lupus. It can affect multiple organ systems and varies person-to-person. While the exact cause is unknown, it is believed that SLE is an autoimmune disorder that causes the body’s immune system to attack other parts of the body. It can manifest with skin changes, kidney problems, heart issues, and generalized symptoms like fatigue and fevers. What are the current mainstay treatments? Currently, treatment is aimed at suppressing the immune system

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Lupus

Mesenchymal Stromal Stem Cells for the Treatment of SLE

Previous studies conducted in China have shown mesenchymal stromal stem cells have the potential to treat patients with lupus and the more severe SLE. However, the results seen in these trials are in patients of similar ethnic backgrounds. New results, of a proof-of-concept study conducted in Spain, were published in Lupus in October, 2018, and support the use of MSCs for the treatment of systemic lupus erythematosus (SLE) in patients with different ethnicities. Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that occurs when your body’s immune system mistakenly attacks your own healthy tissues and organs. The Stem Cells Transplant Institute in Costa Rica, uses human umbilical cord mesenchymal stem cells (hUC-MSCs) for the treatment of systemic lupus erythematosus. Study Design The study, “Therapeutic potential of allogeneic mesenchymal stromal cells transplantation for lupus nephritis,” showed MSCs can control the symptoms of SLE in three patients of different ethnicities who were diagnosed

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depression and lupus risk stem cells Therapy
Lupus

Can Depression Increase the Risk of Developing Systemic Lupus Erythematosus (SLE)?

In a 20-year study of more than 194,000 women, researchers found women with a history of depression have a 2-fold increased risk of developing SLE when compared to women with no history of depression.  Systemic lupus erythematosus is a systemic autoimmune disease that occurs when your body’s immune system mistakenly attacks your healthy tissue and organs. Inflammation caused by SLE can affect your joints, skin, kidneys, blood cells, brain, heart and lungs. The Stem Cells Transplant Institute uses adult mesenchymal stem cells for the treatment of SLE. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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Lupus

Can rheumatoid arthritis, osteoarthritis or lupus increase the risk of developing dementia?

Rheumatic disease is a medical term used to describe many different diseases that affect the joints, muscles and tissues. Some diseases such as osteoarthritis are a result of wear and tear while other diseases such as rheumatoid arthritis, are a result of a problem with the immune system. Stem cell therapy at the Stem Cells Transplant Institute may help reduce the symptoms of rheumatic diseases such as: Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

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