In a 20-year study of more than 194,000 women, researchers found women with a history of depression have a 2-fold increased risk of developing SLE when compared to women with no history of depression. Systemic lupus erythematosus is a systemic autoimmune disease that occurs when your body’s immune system mistakenly attacks your healthy tissue and organs. Inflammation caused by SLE can affect your joints, skin, kidneys, blood cells, brain, heart and lungs. The Stem Cells Transplant Institute uses adult mesenchymal stem cells for the treatment of SLE. Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.