Chronic obstructive pulmonary disease (COPD) has been related to a number of morbidities such as pulmonary embolism, pneumonia, lung cancer, diabetes, osteoporosis and psychological disorders, however, the association of these comorbidities and COPD is not well understood. There has been a lot of variability in the reported prevalence for these comorbidities additionally, smoking is a risk factor for COPD and many of the associated comorbidities, making it difficult to for physicians to understand the relationship between COPD and other disease.
Chronic Obstructive Pulmonary Disease or COPD, is a medical term used to describe a group of chronic, inflammatory lung diseases including; emphysema, chronic bronchitis, refractory asthma and bronchiectasis. It is the fourth leading cause of death in the world.1 The main cause of COPD is long-term exposure to substances that irritate and damage the lungs. Long-term cigarette smoking is the biggest risk factor for developing COPD but additional risk factors include; exposure to second hand smoke, chemical fumes, dust, age and genetics. Asthma and COPD are recognized as distinctly different diseases. Asthma typically starts in childhood and is associated with allergies and eosinophils versus COPD that occurs in adults and involves neutrophils. Asthma and COPD overlap syndrome, or ACOS, describes people who have both diseases. A recent Canadian study found more than 40 percent of women with asthma will develop ACOS. Researchers in Ontario evaluated 4,051 women with asthma. The participants provided their health history and lifestyle. Through a medical database, researchers followed the health histories of the participants between 1992 and 2015. Additionally, using the participants postal code and satellite data, the research team estimated the women’s average exposure to pollution during that time. Out of the more than 4,000 participants, 1,701 women (42%) developed COPD. Risk factors for developing COPD included lower education, being overweight, living in a rural area and smoking. Other studies have shown non-smoking women have a higher rate of COPD than non-smoking men suggesting women may be more susceptible to other COPD risk factors however; men were not included in this study so no comparison can be made. Thirty-four percent of the women that developed ACOS, and 19% of women who did not develop ACOS, died during this study. One of the researchers said patients with ACOS suffer more exacerbations, are hospitalized more frequently and have a lower quality of life compared to patients with asthma or COPD alone. Patients diagnosed with COPD and ACOS are at risk of developing additional complications including:
- Respiratory infections
- Heart problems
- Lung cancer
- High blood pressure in lung arteries
- Easier breathing
- Improved lung function
- Increased energy
- Improved stamina
- Reduced coughing and wheezing
- Reduced number of infections
- Promote self-healing
- Have potent anti-inflammatory capabilities
- Modulate abnormal immune system responses
- Prevent additional premature cell and tissue damage
- Reduce scarring
- Stimulate new blood vessel growth improving blood flow
Teresa To et.al., Asthma and COPD Overlap in Women: Incidence and Risk Factors. Annals of the American Thoracic Society, online July 17, 2018.
Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide and by the year 2020, experts believe it will be the third leading cause of death. Patients with COPD frequently suffer from muscle wasting, a medical condition that occurs when the muscle tissue in the arms and legs atrophies. Peripheral muscle loss and muscle dysfunction is an independent predictor of morbidity and mortality.
Chronic Obstructive Pulmonary Disease (COPD), is a medical term used to describe a group of chronic, inflammatory lung diseases including: emphysema, chronic bronchitis, refractory asthma and bronchiectasis. Conventional therapies include; a combination of pharmaceutical drugs including inhaled corticosteroids, lifestyle changes, oxygen and as a last resort, surgery. Conventional therapies can help alleviate some symptoms of COPD but they do not stop the progression of the disease nor are they curative. The experienced practitioners at the Stem Cells Transplant Institute believe stem cell therapy is a safe and effective alternative to traditional pharmaceutical therapy including inhaled corticosteroids.
Studies demonstrate the effectiveness of stem cell treatment as a way of repairing the damage caused by chronic lung diseases such as COPD. Stem cells have the ability to offset inflammation in the lungs by combining anti-inflammatory and reparative properties to reduce the inflammatory response and restore lung function.