Cardiovascular disease, also called heart disease, is a broad medical term used to describe a group of conditions that affect the blood vessels or the heart. It is the most common cause of death worldwide.1
Conditions of cardiovascular disease include:
The Stem Cells Transplant Institute in Costa Rica, recommends the use of adult mesenchymal stem cells for the treatment of cardiovascular disease (heart disease).
Treatment at the Stem Cells Transplant Institute could help improve the symptoms of cardiovascular disease.
The symptoms of cardiovascular disease will depend on the specific type of heart disease but can include:
Heart disease and cardiovascular disease are often used interchangeably. These terms refer to a group of conditions that affect the blood vessels and heart.
Stem cell therapy may be an effective treatment.
Coronary Artery Disease (CAD)
Coronary artery disease is caused by atherosclerosis, the buildup of plaque, causing a narrowing or blocking the blood vessels in the coronary arteries. Coronary artery disease is the leading cause of cardiovascular disease. Atherosclerosis can lead to chest pain, heart attack or stroke.
Coronary arteries carry oxygen rich blood to the heart. Plaque is caused by the presence of cholesterol, calcium, fat, and other substances in the blood. When plaque builds up in the blood vessels it narrows the arteries causing them to harden and weaken, reducing the amount of oxygen rich blood to the heart. As a result, the heart cannot pump blood effectively to the rest of the body potentially leading to heart failure and ultimately death.
Myocardial infarction (heart attack)
If the plaque building up in the coronary arteries breaks, a blood clot forms around the plaque. If the clot cuts off the blood flow to the heart muscle completely, the heart muscle is unable to get the necessary oxygen and nutrients causing a part of the heart muscle to die. The result is a heart attack or myocardial infarction,
Coronary artery disease, high blood pressure or a previous heart attack can lead to the onset of heart failure. Heart failure is a chronic, progressive disease typically caused by another heart condition resulting in the heart muscle losing its ability to supply the rest of body with enough blood and oxygen.
Peripheral Artery Disease
Atherosclerosis can also cause peripheral artery disease. Peripheral arterial disease occurs when the narrowed peripheral arteries cannot send enough blood flow to the extremities, usually the legs. The most common symptoms of peripheral artery disease are; cramping, pain, and/or tiredness in the leg or hip muscles during exertion. The most severe symptom of peripheral artery disease is critical limb ischemia, pain at rest due to reduced blood flow to the limb.
Approximately 85% of strokes are ischemic strokes. Atherosclerosis is the most common cause of ischemic stroke. If the arteries become too narrow due to plaque buildup, the blood cells may collect and form a clot. A larger clot can block the artery where it is formed (thrombotic stroke) while a smaller clot may travel until it reaches an artery closer to the brain (embolic stroke). When the arteries to your brain become narrow or blocked, the required blood flow is reduced resulting in stroke. Other causes of ischemic stroke are clots due to an irregular heartbeat or heart attack.
Stem cell therapy at the Stem Cells Transplant Institute may be a good alternative for patients seeking a safe, non-surgical treatment for cardiovascular disease.
“Notably, adult stem and progenitor cells including….mesenchymal stem cells have progressed into clinical trials and have shown positive benefits.”5
Stem cell transplantation uses healthy cells to promote the repair of damaged cells and regeneration of healthy and functional cells to repair injured tissue.1
The therapeutic effect of stem cell transplantation in patients with cardiovascular disease may be due to the paracrine effect.
The theory is, transplanted stem cells repair damaged tissue by releasing factors that promote regeneration of healthy stem cells, reduce inflammation, promote the growth of new blood vessels, inhibit cell death, and reduce hypertrophy.1
According to Clincialtrials.gov (https://clinicaltrials.gov), currently there are more than 1,130 clinical trials evaluating stem cell therapy for the treatment of cardiovascular disease.
The results of initial research using mesenchymal stem cell transplantation are provided below.
Myocardial Infarction (Heart attack, MI)1,5,8
Peripheral Artery Disease (PAD)5-7
Mesenchymal stem cells
Several months following treatment, stem cells continue to migrate to the heart muscle regenerating and renewing healthy heart function.
Stem cell therapy cannot help all patients with cardiovascular disease but for many patients stem cell therapy combined with lifestyle modification may be a safe, effective, non-surgical alternative treatment.
Lifestyle changes that can help improve cardiovascular disease include:
For optimal results, the Stem Cells Transplant Institute recommends the use of hUC-MSCs for the treatment of cardiovascular disease.
If the patient prefers, autologous mesenchymal stem cells derived from the patient’s own adipose tissue and bone marrow, can also be used to treat cardiovascular disease.
Umbilical cord stem cells
We use only umbilical cord stem cells that are derived exclusively from umbilical cord donations.
The umbilical cord stem cells from are collected after informed consent has been given by the parent, or parents, and only after the delivery of the baby.
The collection follows strict ethical protocols ensuring the stem cells are from safe, reliable sources using a non-invasive, simple and painless procedure. Once collected, the cord blood is then screened for disease.
Autologous adipose and bone marrow stem cells
On the day of the procedure, under local anesthesia and sterile conditions, a small sample of bone marrow is removed from the hip and a small of amount of adipose tissue (fat) is removed from the abdomen.
The stem cells are administered intravenously.
Costa Rica has one of the best healthcare systems in world and is ranked among the highest for medical tourism.
Using the most advanced technologies, the team of experts at The Stem Cells Transplant Institute believes in the potential of stem cell therapy for the treatment of cardiovascular disease.
We are committed to providing personalized service and the highest quality of care to every patient.
Contact us to see if stem cell therapy may be a treatment option for you.