Regenerate. Repair. Restore.

Stem Cells Therapy for Neuropathy And Diabetic Neuropathy

What is Neuropathy?

Neuropathy is a condition in which one or more nerves are damaged or dysfunctional, causing numbness, tingling, muscle weakness, and pain in affected areas.

Diabetic neuropathy is a common and serious diabetic condition that damages the nerves throughout the body due to persistent high levels of blood sugar (glucose). Diabetic neuropathy symptoms can range from mild to severe, depending on which nerves are affected.

According to the National Institute of Diabetes and Digestive and Kidney Disease, diabetic neuropathy affects 60-70% of people with type 1 and type 2 diabetes.

Risk factors of neuropathy:

  • Alcoholism
  • Bone marrow disorders
  • Autoimmune disease
  • Kidney disease
  • Liver disease
  • Hypothyroidism
  • Idiopathic: no known cause
  • Infections
  • Inherited disorders
  • Medications
  • Poisons
  • Trauma
  • Tumors
  • Vitamin deficiency
  • Viruses

Types of neuropathy:

  1. Peripheral neuropathy
  2. Proximal neuropathy
  3. Autonomic neuropathy
  4. Focal neuropathy
  5. Cranial neuropathy

It is possible to have one or more of the four types of neuropathies. Neuropathies can be confusing, difficult to diagnose accurately, and extremely painful.

Diabetic neuropathy can lead to other serious medical conditions including:

  • Heart attack
  • Digestive issues
  • Foot ulcers
  • Amputation
  • Increased difficulty controlling blood sugar levels

Causes of neuropathy?

Causes of neuropathy include diabetes, chemo-induced neuropathy, genetics, inflammatory infections, auto-immune diseases, protein abnormalities, toxic chemicals, poor nutrition, alcoholism, medications, and kidney failure.

Although the exact cause of diabetic neuropathy is still unknown, scientists believe it is caused due to high blood sugar levels. Other contributing factors include inflammation, high cholesterol levels, high triglycerides, elevated blood pressure, smoking and obesity. Evidence suggests that the nerve damage begins early in the disease and individuals with prediabetes already have some nerve damage. Diabetic neuropathy affects children, teens and adults.

How can stem cells improve the symptoms of neuropathy or diabetic neuropathy?

Research shows that stem cells improve neuropathy by directly modulating both, angiogenesis (the physiological process through which new blood vessels form) and myelination (the process of myelin sheath formation around a nerve to allow nerve impulses to move more quickly).

There are currently 47 studies listed on evaluating the safety and or efficacy of stem cells for the treatment of diabetic neuropathy. (

Mesenchymal stem cells are self-renewing cells that can be found in almost all organs and tissues, including bone marrow, adipose tissue, umbilical cord blood, compact bone, and others.

Based on clinical research, the Stem Cells Transplant Institute in Costa Rica recommends the use of umbilical cord derived mesenchymal stem cells for the treatment of diabetic neuropathy.

About the Stem Cells Transplant Institute

Costa Rica has one of the best healthcare systems in world and is ranked among the highest for medical tourism.

Using the most advanced technologies, the team of experts at The Stem Cells Transplant Institute believes in the potential of stem cell therapy for the treatment of neuropathies.

We are committed to providing personalized service and the highest quality of care to every patient.

Scientific References:

  1. National Institute of Diabetes and Digestive and Kidney Disease. Diabetic neuropathies: The nerve damage of diabetes. Accessed March 6, 2017.