Stem Cells Therapy
for
Cranial neuropathy

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Neuropathies are characterized by damage to the nerves. There are four types of neuropathy; peripheral, proximal, focal, and autonomic. Cranial neuropathy is a type of focal neuropathy.

Cranial neuropathy occurs when one or more of the twelve nerves that exit the brain are damaged. The symptoms of cranial neuropathy will depend on which nerve is affected.

Treatment at the Stem Cells Transplant Institute could help improve the symptoms of cranial neuropathy including:

  • Sharp, jabbing or throbbing pain
  • Drooping of the facial muscle
  • Tingling
  • Numbness
  • Loss of vision
  • Double vision
  • Abnormal movement of the eye
  • Blurred vision
  • Increased pupil size
  • Droopy eyelid
  • Weak or paralyzed muscles
  • Skin that is sensitive to touch

What is cranial neuropathy?

Neuropathy is a general term to used describe any condition that results in damage to one or more nerves. Injury or disease can damage the nerves at any location and the type of neuropathy is typically classified by the location of the damaged nerves or by the disease causing the damage.

Cranial neuropathy occurs when one or more of the twelve nerves that exit the brain, or brain stem, are damaged.

Types of cranial neuropathies include:

  • Bell’s palsy: This condition occurs when the facial nerve, or seventh cranial nerve, is affected.
  • Microvascular cranial nerve palsy: This condition affects the nerves in the eye. It is most common in people who have diabetes and in those who have high blood pressure.
  • Third nerve palsy: This condition affects the third cranial nerve. This nerve helps manage a muscle that controls eye movement.
  • Fourth nerve palsy: This is also called superior oblique palsy. It affects the superior oblique muscle, which helps you converge your eyes (to look at the tip of your nose).
  • Sixth nerve palsy: This is also called cranial nerve VI or abducens palsy. It affects the sixth cranial nerve, which also helps control eye movement.
  • Multiple cranial neuropathies:several different cranial nerves are affected

Possible causes of cranial neuropathy include:

  • Diabetes
  • High blood pressure
  • Migraine headaches
  • Infections
  • Inherited disorders
  • Tumor
  • Trauma
  • Virus

What do we know about cranial neuropathy?

Sometimes medicines can be used to treat an infection, help reduce swelling in, or near a nerve, or help if the neuropathy is causing pain. In some cases, surgery may help. Other times, the nerve damage can’t be treated or repaired.

How can stem cell therapy improve the symptoms of cranial neuropathy?

Mesenchymal stem cells produce;

  1. proteins that support the growth and survival of neurons
  2. angiogenic factors that are essential for the healing, growth, development, and maintenance of blood vessels
  3. immunomodulatory substances that can reverse the damage to the nerves

What is the treatment protocol for cranial neuropathy at the Stem Cells Transplant Institute?

The Stem Cells Transplant Institute recommends the use of hUC-MSCs for the treatment of neuropathy.

Treatment includes:

  1. 1cc vial of 30 million mesenchymal stem cells derived from human umbilical cord blood
  2. Antioxidant therapy with vitamin C and glutathione
  3. Ozone therapy
  4. Platelet-rich plasma therapy (PRP)

What are the advantages of human umbilical cord mesenchymal stem cells?

  • Abundant supply containing up to 10 times more stem cells than bone marrow or adipose derived stem cells
  • hUC-MSC have immunosuppressors and immunomodulatory properties that allow their use in any individual without rejection- Human Leukocyte Antigen (HLA) matching is not necessary
  • Greater proliferation ability than adult autologous stem cells
  • They regenerate at a very rapid rate
  • They are young and very adaptive
  • They have not been impacted by the aging process
  • They have not been affected by environmental toxins
  • Umbilical cord stem cells can be administered multiple times over the course of days
  • Eliminates the need to collect stem cells from the patient’s fat or hip bone reducing pain and recovery time

How are the stem cells collected?

We use only umbilical cord stem cells that are derived exclusively from umbilical cord donations. 

The umbilical cord stem cells from are collected after informed consent has been given by the parent, or parents, and only after the delivery of the baby.

The collection follows strict ethical protocols ensuring the stem cells are from safe, reliable sources using a non-invasive, simple and painless procedure. Once collected, the cord blood is then screened for disease.

How are the stem cells administered?

The stem cells are administered by intrathecal and intravenous injection.

About the Stem Cells Transplant Institute

Costa Rica has one of the best healthcare systems in world and is ranked among the highest for medical tourism.

Using the most advanced technologies, the team of experts at The Stem Cells Transplant Institute believes in the potential of stem cell therapy for the treatment of neuropathy.

We are committed to providing personalized service and the highest quality of care to every patient. Contact the experts at the Stem Cells Transplant Institute to see if stem cell treatment might help you.

Scientific References:

  1. Cell Death Discovery (2016) 2, e16055; doi:10.1038/cddiscovery.2016.55; published online 11 July 2016 Mesenchymal stem cells to treat diabetic neuropathy: a long and strenuous way from bench to the clinic JY Zhou
  2. Han, JW et al., Bone Marrow-Derived Mesenchymal Stem Cells Improve Diabetic Neuropathy by Direct Modulation of Both Angiogenesis and Myelination in Peripheral Nerves. Cell transplant.2016;25(2):313-26. doi: 10.3727/096368915X688209. Epub 2015 May 13
  3. Vickers RE et al., A preliminary report on stem cell therapy for neuropathic pain in humans. J Pain Res. 2014; 7: 255–263. Published online 2014 May 8.