In recent years, the regenerative medicine world has seen an emerging trend of natural healing substances called “exosomes.” Numerous studies are being conducted to test their safety and efficacy and they are gradually replacing the hype of stem cell therapy. Exosomes have significant implications in regenerative medicine – from playing a major role in regeneration to boosting healing properties of the immune system.
What Are Exosomes?
Exosomes are defined as “extracellular vesicles” – a part of the cell that plays a critical role in intracellular (cell to cell) communication. These are called extracellular vesicles because the cells naturally release them outside the cell to regulate and maintain certain functions related to healing and regeneration. ‘
When cells release exosomes, they carry specific proteins and genetic information to neighboring cells. This intracellular communication is important for the transportation of molecules essential for regulating cell-to-cell information. This essentially means that exosomes carry information in the form of proteins that tells adjacent and distant cells how to react.
Certain factors such as age, illness, and genetic disorders can disrupt the mechanism cells normally use to communicate with one another. Such disruption can cause a number of both physical and mental ailments.
Therapeutic Potential Of Exosomes
Numerous medical studies and clinical trials have linked exosomes to several important roles in the body. Exosomes released from specific cell types perform several functions such as stimulating regeneration in many tissues.
Similarly, exosomes also work in regenerative medicine in multiple ways. In a study, when exosomes of a younger organism were injected into the cells of an older organism, they were linked to the rejuvenation of the older cells. Furthermore, exosomes can benefit degenerative diseases (such as arthritis) by breaking the degenerative cycle.
Degenerative damage to the cells cause decreased secretion of the exosomes necessary to promote healing. One study found that introducing exosomes to damaged tissue can stimulate the healing process and boost regeneration.
Another benefit of exosome therapy is its usefulness in drug delivery. Hopefully, in the near future, scientists and physicians will be able to use exosome-based medicines for targeted drug delivery. This could also transform the current treatment for cancer and other body conditions that require targeted delivery of the drugs. Currently, patients with cancer receive multiple doses of chemotherapy and radiotherapy. However, these drugs and rays are fatal to healthy body parts and can cause more damage to the patient. Exosomes can be the next step in the targeted drug delivery system and may specifically target tumor cells in the future. Furthermore, exosomes may help deliver drugs to the brain and other organs of the body with a blood-organ barrier. Speaking of the brain, this would be a revolution as there are no safe and effective ways to deliver medicine to the brain.
At the moment, exosomes are not well understood and several studies are underway to discover more about them. However, from what we currently know, there are numerous positive implications and health benefits of exosomes for the future. These extracellular vesicles have the potential to become a key component in targeted drug delivery and regenerative medicine.
Get The Help And Support You Need
At the Stem Cell Transplant Institute, we are delivering high-quality and cost-effective exosome therapy to target diseased tissues or organs. We use exosomes released by the regenerative stem cells to help boost the healing and repair process. Furthermore, you can use our therapy to treat orthopedic injuries and disorders such as arthritis, infections (toxoplasmosis, diphtheria, tuberculosis), and reduce the signs of aging. Please contact us for more information.
Since exosomes appear to be part of stem cell treatment, a natural adjunct, change the “hype” sentence to this: “Numerous studies are being conducted to test their safety and efficacy and they are currently a natural adjunct to stem cell therapy.”