Human Umbilical Cord Tissue Mesenchymal Stem Cells the New “Gold Standard” for Stem Cell Therapy

Regenerative medicine may be the best hope for patients with a chronic disability or disease. Stem cells are being used to treat neurological, cardiovascular, autoimmune and orthopedic conditions as well as spinal cord injuries, severe wounds, erectile dysfunction and the list goes on.

Note: Despite all advances in stem cells research and the application of these therapies in many countries all over the world, stem cells therapies are not legally approved yet in San Diego, Los Angeles, Chicago, Dallas, New York, Jacksonville, Seattle, Houston, San Francisco, Salt Lake City, Miami, Beverly Hills and other US cities. However, stem cell treatments are legal in Costa Rica.

By regenerating tissue and organs, and reducing inflammation, human umbilical cord tissue mesenchymal stem cells (HUCT-MSCs) have demonstrated they have the ability to improve conditions that currently have no, or few, treatment options.

Mesenchymal stem cells repair damaged tissue and organs, repair function, modulate the immune system and reduce inflammation. The most powerful and abundant source of mesenchymal stem cells is found in gelatin of Wharton’s jelly in the the tissue of umbilical cords.

In September of 2018, researchers published the results of their evaluation of more than 30 studies evaluating the regenerative benefits of Wharton’s jelly, stem cells derived from the umbilical cord blood and tissue and other products derived from the umbilical cord.

Umbilical cord tissue

Previously umbilical cord tissue was considered medical waste and discarded, however, today experts in the field of regenerative medicine, are preserving and using umbilical cord tissue to treat injuries and chronic, degenerative conditions.

Wharton’s jelly is the gelatinous substance in the umbilical cord that protects and insulates the blood vessels. The jelly is made up of hyaluronic acid, chondroitin sulfate, collagen, fibrin, fibroblasts, macrophages and expresses stem cells including mesenchymal stem cells and telomerase.

The review of available data, published in Stem Cell Research & Therapy, evaluated the benefits of products obtained from Wharton’s jelly and discussed their potential clinical applications.

Wharton’s jelly can be used in several ways including: 1. The matrix surrounding the cells is made up of hyaluronic acid, collagen and fibrin that can be used to treat burns and wounds. The jelly is applied to the damaged area to accelerate tissue restoration and 2. Adult mesenchymal stem cells can be isolated, cultured and expanded to treat diseases such as Alzheimer’s, Parkinson’s, MS, Autism, spinal cord injury, rheumatoid arthritis, diabetes, traumatic brain injury.

Mesenchymal Stem Cells Derived from Wharton’s Jelly

The results of the data analysis showed the properties of mesenchymal stem cells derived from Wharton’s jelly exceed those of stem cells derived from bone marrow and adipose tissue. HUCT-MSCs have been shown to reduce inflammation, modulate the immune system, and repair damaged tissue.

HUCT-MSCs proliferate and differentiate more efficiently and effectively than cells found in bone marrow and adipose tissue, and umbilical cord tissue is a more abundant source of mesenchymal stem cells than the blood of the umbilical cord.

Mesenchymal stem cells from the umbilical cord have immunosuppressors and immunomodulatory properties that allow their use in any individual without rejection. The cells do not express HLA-DR the antigen responsible for rejection. 

Current Research

Researchers are conducting clinical trials to evaluate the efficacy of stem cells derived from umbilical cord blood, and umbilical cord tissue. Some of the research includes:

Stem cells from umbilical cord tissue:

  1. Systemic lupus erythematosus
  2. Multiple sclerosis
  3. Autism
  4. Alzheimer’s disease
  5. Spinal cord injury
  6. Type I and type II diabetes
  7. Rheumatoid arthritis
  8. Cardiomyopathy
  9. Muscular dystrophy
  10. Hepatic failure and liver cirrhosis
  11. Graft versus host disease (GVHD)
  12. Critical limb ischemia
  13. Burns
  14. Osteoarthritis

Stem cells from umbilical cord blood:

  1. Cerebral palsy
  2. Ischemic stroke
  3. Traumatic brain injury
  4. Alzheimer’s disease
  5. Crohn’s disease
  6. Type I and Type II diabetes
  7. Rheumatoid arthritis

Stem Cell Therapy at the Stem Cells Transplant Institute

At the Stem Cells Transplant Institute in Costa Rica we recommend umbilical cord stem cells for the treatment of Alzheimer’s disease, Parkinson’s disease, lupus, rheumatoid arthritis, multiple sclerosis, myocardial infarction, stroke, diabetes (type I and type II), spinal cord injury, neuropathy, COPD, and ALS.

  • Our physicians are accredited by the American Academy of Anti-Aging and Regenerative Medicine
  • We collaborate with the leading researchers, laboratories and clinics worldwide
  • Our physicians are members of the International Society for Stem Cell Application, and our CEO and founder, is the ISSCA Chapter Director for Central America and the Caribbean.
  • We utilize cutting edge procedures that mix adipose derived mesenchymal stem cells with platelet rich growth factors to enhance efficacy and improve outcomes
  • We use adult mesenchymal stem cells derived from the human umbilical cord, or from a patient’s own tissue.
  • Our physicians are fully licensed to practice medicine and perform stem cell treatments in Costa Rica.
  • Stem cell treatment at the Stem Cells Transplant Institute may be significantly less expensive than similar treatments available in the United States, Europe, Mexico and Asia
  • We promise to treat every patient with care and respect.
  • We promise to do everything within our power to assist our patients and answer your questions thoroughly and honestly.

At the Stem Cells Transplant Institute, we tailor each stem cell treatment, based on the patient’s individual needs and goals.

Human umbilical cord mesenchymal stem cells and autologous mesenchymal stem cells have been proven in clinical trials to be safe and effective.

The mission of the Stem Cells Transplant Institute in Costa Rica, is to provide the highest level of care, using the most advanced technologies, to every patient that wants to experience the life changing benefits of stem cell therapy.

Contact us today to learn more about the power of stem cell therapy.

Scientific Publications

  1. Arutyunyan et al., Umbilical cord tissue cryopreservation: a short review. Stem Cell Research & Therapy (2018) 9:236.
  2. Arutyunyan I, Elchaninov A, Makarov A, Fatkhudinov T. Umbilical cord as prospective source for mesenchymal stem cell-based therapy. Stem Cells Int. 2016;2016:6901286.
  3. Kalaszczynska I, Ferdyn K. Wharton’s jelly derived mesenchymal stem cells: future of regenerative medicine? Recent findings and clinical significance. Biomed Res Int. 2015;2015:430847.
  4. Ding DC, Chang YH, Shyu WC, Lin SZ. Human umbilical cord mesenchymal stem cells: a new era for stem cell therapy. Cell Transplant. 2015;24(3):339– 47.