Stem cells can slow or reverse the signs of aging, by regenerating and repairing tissue and organs damaged by stress and environmental toxins, improving immune function and reducing inflammation. The Stem Cells Transplant Institute, in Costa Rica, uses adipose derived stem cells to treat the signs and symptoms of aging.
What happens to our cells as we age?
Every organ in our body is made up of cells including the heart, liver, kidney and brain. DNA makes up the cells in our body and DNA is protected by telomeres. Telomeres are like the plastic caps on the end of a shoelace, protecting the DNA from damage. As cells are damaged or destroyed, surrounding cells replicate to make new cells. During cell replication, the telomeres allow the chromosome to be replicated correctly however, each time a cell is replicated the telomere is shortened a little bit. When your shoelace loses the plastic end it begins to fray and unravel. When a telomere is too short, it can no longer do its job, causing the cell to die or become pro-inflammatory; beginning the ageing process.3-6
Researchers have found stress can be a predictor of shorter telomere length. When we expose our bodies to chronic stress the result is shorter telomeres and early aging. Telomere shortening is involved in the aging process at a cellular level. The result of chronic stress is systemic damage that requires increased cell replication which ultimately speeds up the aging process.1-3 Stem cell therapy at the Stem Cell Transplant Institute can slow or reverse the aging process by inserting new, healthy cells.
Adipose derived mesenchymal stem cell vs bone marrow derived stem cell- which type of stem cell is best?
Through a process called differentiation, stem cells have the unique ability to become many types of cells such as skin, brain and heart cells. Both bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells are being studied for their safety and efficacy in a range of anti-aging or regenerative medicine therapies, but which type of cell is best? Researchers in the division of Regenerative Medicine in the school of Biological Sciences at the University of Manchester conducted a study comparing the two types of stem cells. The results showed adipose derived stem cells were able to proliferate faster, retain their ability to differentiate longer and adipose derived stem cells had a higher mean telomere length than bone marrow derived stem cells. If adipose derived stem cells can replicate cells that have a longer telomere and can replicate faster for a longer period of time, they may be the most appropriate cell type for regenerative medicine therapies.4
When our cells die what happens to our bodies?
- Hair gradually thins.
- Skin produces less oil becoming drier, thinner, and less elastic.
- Metabolism slows increasing body fat and decreasing muscle mass.
- Heart rate slows and the heart may become bigger.
- Blood vessels and arteries become stiffer making the heart work harder.
- Bones shrink in size and density becoming weaker.
- Muscles lose strength and flexibility.
- Memory is less accurate and less efficient.
- Hearing is reduced with high frequency sounds harder to hear.
- Changes in circadian rhythm resulting in sleeplessness at night and increased fatigue.
- Changes in sexual drive and/or performance.
How does regenerative medicine work?
The Stem Cells Transplant Institute uses adult autologous stem cells derived from the patient’s own adipose tissue. The stem cells are collected from the patient, reprogrammed in the lab and then delivered back into the patient. The healthy cells replace the damaged cells boosting the body’s natural ability to heal itself. Tissue and organ function is restored resulting in improved immune function and decreased inflammation. Patients may experience increased energy, improved hair quality, younger looking skin, improved organ function, reduced joint pain and stiffness and improved mental function. Contact the experts at the Stem Cells Transplant Institute to learn more about the benefits of regenerative medicine.
References:
- Jaskelioff M, et al. Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. 2011;469:102–107.
- Blackburn EH, Epel ES. Comment: Too toxic to ignore. 2012;490:169–171.
- Armanios M, Blackburn EH. The telomere syndromes. Nature Reviews Genetics.2012;13:693–704.
- Burrow, KL., et. al., Human Adipose-Derived Stem Cells Exhibit Enhanced Proliferative Capacity and Retain Multipotency Longer than Donor-Matched Bone Marrow Mesenchymal Stem Cells during Expansion in Vitro. Stem Cells Intl., vlm 2017, Article ID 2541275, 15 pages, https://doi.org/10.1155/2017/2541275