What is the objective of Stem Cells Transplat Institute?

Stem Cells Transplat Institue transplant institute under the direction of Dr. Mesén has the mission to provide to its patients the highest standards of quality, service, lawfulness, honesty and human resource, so they can opt for these life-changing therapies; as well as to contribute with the expansion of this medical trend.

What differentiates stem cells from other cells?

Stem cells are distinguished from other cell types by two important characteristics. First, they are unspecialized cells capable of renewing themselves through cell division. Second, under certain physiologic conditions, stem cells can be induced to become tissue- or organ-specific cells with special functions. In some organs, such as the gut and bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues.

Nowadays, we know that stem cells are not only in the umbilical cord, but we can find them in all human body tissues. Stem cells are now isolated from adult specialized cells and there has been a continuing expansion in the number and type of stem cells under study.

What are the benefits stem cell treatment?

Stem cells therapies have been expected to bring substantial benefit to patients suffering a wide range of diseases and injuries. For example, benefits of cells transplantation for patients needing reconstruction of their immune systems, would apply to stem cell transplants of other cell types, and optimism has been high for the utilization of pluripotent stem cell types for a variety of applications.

Clinical investigations using stem cell products in regenerative medicine are addressing a wide spectrum of conditions using a variety of stem cell types. Many stem cells administered show transient presence for a few days with trophic influences on immune or inflammatory responses.

Stem cells and their differentiated progeny offer great hope for treating disease by providing an unlimited source of cells for repairing or replacing damaged tissue. Initial studies suggested that, unlike ‘normal’ transplants, specific characteristics of stem cells enabled them to avoid immune attack, providing more effective transplants.

What diseases can be treated with stem cells?

The ability of stem cells to turn into any cell type that the body needs means that they have major potential to treat diseases where tissue has been damaged. This is an exciting and promising area for medicine that may revolutionize the treatment of many diseases in the coming decades such us Alzheimer, Parkinson, Multiple sclerosis, Lupus, Rheumatoid arthritis, Osteoarthritis, COPD, Diabetes, Neuropathy, Heart disease, Congestive heart failure, Myocardial infarction, Critical limb ischemia and Erectile dysfunction.

The use of stem cells as a treatment is a revolutionary idea of the XXI century, which has become a reality nowadays.

How stem cells are classified?

Stem cells can be classified into four broad types based on their origin. Stem cells from embryos; stem cells from the fetus; stem cells from the umbilical cord; and stem cells from the adult. Each of these can be grouped into subtypes.nipotent cells pluripotent,and  epidermal, neuronal, eye, gut..)ls.. For example, adult stem cells are divided in germline and somatic (hemopoietic, mesenchymal, liver, epidermal, neuronal, eye, gut..)

Stem cells can also be classified according to its plasticity in totipotent, pluripotent, multipotent and unipotent cells. Totipotent stem cells have the potential to generate all the cells needed for human development, plus the extra embryonic, or placental, cells. Embryonic cells within the first couple of cell divisions after fertilization are the only cells that are totipotent. Pluripotent stem cells can give rise to all of the cell types that make up the body; embryonic stem cells are considered pluripotent. Multipotent stem cells can develop into more than one cell type, but are more limited than pluripotent cells; adult stem cells and cord blood stem cells are considered multipotent. They are found in specific organs and can only become cells within that organ; for example, multipotent stem cells in the brain can become nerve cells or other brain cells. These cells do have the potential to maintain and repair particular organs and tissues. Unipotent stem cells can be differentiated along only one lineage.

Finally, stem cells can be classified deepening on the source in autologous (cells from the same individual), allogenic (cells from the same species) and xenogeneic (cells from different species).

Neural stem cells show considerable promise for regenerative repair, pluripotent stem cells have an abundant potential in regenerative medicine, and mesenchymal stem cells are numerically the most favored cell type presently under clinical trial.